<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y   K101E, Y188H, G190A E138K V35E, T39A, E44D, V118I, K122E, I142T, K173N, V179VI, Q197K, T200A, I202V, Q207E, R211K, V245Q, I257L, K277R, I293V, T296S, E297K, Q334L, R356K, R358K, K390KR  
>05603A| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALEEICAELEKDGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNKTPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRNQNPDIII
YQYVDDLHVASDLEIGKHRAKVEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDLQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLSKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYAKMKGA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I47V, I54M, L90M V11I, L33F, K43T, G73A L10I, I13V, N37D, I62V, L63P, I64V, A71T, I72T, V77I, I93L  
>05603A| codons 1-99
PQITLWQRPIITVKIGGQLKEALLDTGADDTVFEEMDLPGRWTPKMVGGIGGFMKVRQYD
QVPVEICGHKTTATVLIGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010