Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | L10F, L89V | I13V, K20I, E35D, M36I, N37D, L63P, A71V, Q92K, C95L |
| >05602A| codons 1-99 PQITLWQRPFVTVKIGGQLIEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFVKVRQYD QIPIEICGHKVIGTVLVGPTPVNVIGRNVMTKIGLTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K20R, V35I, T39A, K43E, E44D, R83K, V118I, K122KE, D123E, K173Q, Q174K, G196E, T200I, Q207E, R211K, D218E, A272P, T286P, I293V, T296S, E297K, K311KR, D324E, G333E, Q334Y, R356K, M357R, R358K, G359S, A360T, T386I |
| >05602A| codons 1-399 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICAELEEDGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRQKNPDIVI YQYVDDLYVGSDLEIEQHRIKIEELREHLWKWGFYTPEKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGPKALTEVVPLSKEAE LELAENREILREPVHGVYYDPSKELIAEIQKQEYGQWTYQIYQEPFKNLKTGKYAKRKST HTNDVKQLTEAVQKIATESIVIWGKIPKFKLPIQKETWE |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |