<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, L210W, T215Y   K101E, Y181C, G190A V108I K20R, V35E, T39E, E40F, K103KR, V118I, K122E, I142V, D177E, I178M, V189I, E203K, Q207E, H208Y, R211K, K223Q, V245M, A272P, K277R, T286P, E297A, S322T, I329V, A360T, A371V, A376T, T386TA  
>05571A| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALEEICEFLEKEGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKRKSVTILDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
CQYMDDLYIASDLEIGQHRTKIKELREYLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGPKALTEVIPLTAEAE
LELAENREILKEPVHGVYYDPTKDLIAEVQKQGQGQWTYQIYQEPFKNLKTGKYARMRGT
HTNDVKQLTEVVQKITTESIVIWGKAPKFKLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54A, V82A L24I, L33F L10I, G16A, N37S, R41K, L63P, A71V, I72V, V77I, T91A, Q92K  
>05571A| codons 1-99
PQITLWQRPIVTIKIAGQLKEALIDTGADDTVFEEMSLPGKWKPKLIGGIGGFAKVRQYD
QIPIEICGHKVVGTVLIGPTPANIIGRNLLAKIGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010