Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI|NRTI|PI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, L210W, T215Y | K101E, Y181C, G190A | V108I | K20R, V35E, T39E, E40F, K103KR, V118I, K122E, I142V, D177E, I178M, V189I, E203K, Q207E, H208Y, R211K, K223Q, V245M, A272P, K277R, T286P, E297A, S322T, I329V, A360T, A371V, A376T, T386TA |
| >05571A| codons 1-400 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALEEICEFLEKEGKISKIGPENPYNTPV FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKRKSVTILDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI CQYMDDLYIASDLEIGQHRTKIKELREYLWKWGFYTPDKKHQQEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGPKALTEVIPLTAEAE LELAENREILKEPVHGVYYDPTKDLIAEVQKQGQGQWTYQIYQEPFKNLKTGKYARMRGT HTNDVKQLTEVVQKITTESIVIWGKAPKFKLPIQKETWEA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54A, V82A | L24I, L33F | L10I, G16A, N37S, R41K, L63P, A71V, I72V, V77I, T91A, Q92K |
| >05571A| codons 1-99 PQITLWQRPIVTIKIAGQLKEALIDTGADDTVFEEMSLPGKWKPKLIGGIGGFAKVRQYD QIPIEICGHKVVGTVLIGPTPANIIGRNLLAKIGCTLNF |
References
| Author | Title | Citation |
| Dau, B | Connection domain mutations in treatment-experienced patients in the OPTIMA trial. | JAIDS, 2010 |