<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R T215I, K219E, N348I Y188L   T39A, T69TN, A98S, K122KE, I135T, I142V, T200A, F214FL, A272P, K277Q, K281R, T286A, V292I, I293V, E297R, D324E, Q334N, A376V, E396D  
>05500A| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLLVGSDLEIGQHRAKIEELRQHLLRWGLITPDEKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVQQLCRLLRGAKALTEIVPLTREAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGNGQWTYQIYQEPFKILKTGKYARMRGA
HTNDVKQLTEAVQKIVTESIVIWGKTPKFKLPIQKDTWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, L90M L10F I13V, K55R, I62V, L63P, I64V, T74S, V77I, I93L  
>05500A| codons 1-99
PQITLWQRPFVTVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVRVRQYD
QVPVEICGHKAIGSVLIGPTPTNIIGRNLMTQLGCTLNF

References
Author Title Citation
Dau, B Connection domain mutations in treatment-experienced patients in the OPTIMA trial. JAIDS, 2010