<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 23
2 3TC+AZT+EFV 41

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215F   K101E, Y188L   V35T, T39E, S68G, K122E, D123N, I135R, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, V245E, E248D Y127F
>079-008-008| codons 20-263
KVKQWPLTEEKIKALTEICEELEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRE
LNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPLDENFRKFTAFTIPSRNNET
PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVIYQYVDDLLVGSDLEIGQHR
AKIEELRAHLLSWGFFTPDKKHQKEPPFLWMGYELHPDKWTVQPIELPDKDSWTVNDIQK
LVGK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12P, I13V, I15V, G16E, E35D, M36I, R41K, R57K, Q61E, H69K, K70R, L89M  
>079-008-008Pr| codons 1-99
PQITLWQRPVVPVKVEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
EILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Bunupuradah, T Etravirine and rilpivirine resistance in HIV-1 subtype CRF01_AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens. Antivir Ther, 2011