Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LB3-P11 | P11-9 | U.S. | 1997 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | EFV+IDV | 9 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, N37D, L63S, I64V, Q92K |
| >P11-9| codons 1-99 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QISVEICGHKAIGTVLVGPTPVNIIGRNLLTKIGCTLNF >P11-9| F04 | codons 1-99 | clone F04 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QISVEICGHKAIGTVLVGPTPVNIIGRNLLTKIGCTLNF >P11-9| F01 | codons 1-99 | clone F01 PQITLWQRPLVTVKIEGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYD QISVEICGHKAIGTVLVGPTPVNIIGRNLLTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | K103N | E42D, T69N, R83K, E169D, E194K, G196E, T200A | D113G |
| >P11-9| codons 1-229 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMDKEGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGGAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLKIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P11-9| F04 | codons 1-229 | clone F04 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P11-9| F01 | codons 1-229 | clone F01 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMDKEGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGGAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLKIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLW |
References
| Author | Title | Citation |
| Bacheler, LT | Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy. | AAC, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |