Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LB3-P1 | P1-36 | U.S. | 1997 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | EFV+IDV | 36 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10I, E35D, M36I, I62V, L63P, A71V, V77I, I93L |
| >P1-36| A08 | codons 1-99 | clone A08 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| A01 | codons 1-99 | clone A01 PQITLWQQPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| A06 | codons 1-99 | clone A06 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| A03 | codons 1-99 | clone A03 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRTLLTQLGCTLNF >P1-36| A09 | codons 1-99 | clone A09 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| A10 | codons 1-99 | clone A10 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| A02 | codons 1-99 | clone A02 PQITLRQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| A05 | codons 1-99 | clone A05 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF >P1-36| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVISTVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184I, L210W | K70Q, T215D | K103N | E40F, K43E, V118I, G196E, K201I, H208F, R211K |
| >P1-36| A09 | codons 1-229 | clone A09 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAFLEEEGKISKIGPENPYNTPV FAIKKKNSTQWRKLMDFRELNKRTQDFWKVQLGIPHPAGLKKNKSVTVLDVGDTYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRIKIEELREHLWKWGFYTPDKKHQKEPPFLW >P1-36| A05 | codons 1-229 | clone A05 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNSTQWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW >P1-36| A06 | codons 1-229 | clone A06 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKIPKIGPENPYNTPV FAIKKKNSTAWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW >P1-36| A03 | codons 1-229 | clone A03 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNSTQWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQTEPPFLW >P1-36| A08 | codons 1-229 | clone A08 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNSTQWRKLMDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW >P1-36| A01 | codons 1-229 | clone A01 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNSTAWRKLMDFRELNKRTQGFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDGLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW >P1-36| A02 | codons 1-229 | clone A02 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNSTQWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNGTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW >P1-36| A10 | codons 1-229 | clone A10 PISPIETVPVKLKPGMGGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNGTQWRKLMDFRELNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW >P1-36| codons 1-229 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTFLEEEGKISKIGPENPYNTPV FAIKKKNSTQWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIEQHRTIIEELRQFLWKWGFDTPDKKHQKEPPFLW |
References
| Author | Title | Citation |
| Bacheler, LT | Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy. | AAC, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |