<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  T66S V31I, M50T, I72V, P90S, F100Y, L101I, T112V, S119P, T124N, T125A, K136Q, V201I, I203M, T218I, I220V, L234I, R269K, D278A S283G
>SK184| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI
WQLDCSHLEGKVILVAVHVASGYIEAEVISAETGQETAYYILKLAGRWPVKVIHTDNGPN
FTSNAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQIIKVQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, M36I, R41K, L63T, H69K, V82I, I93L  
>SK184| codons 1-99
PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPINIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39E, S48T, V60I, K122A, K173T, Q174K, D177E, T200E, Q207E, R211K, V245Q, D250N, A272P, E291D, V292I, I293V, E297V, S322P, Q334D, G335D, R356K, M357R, G359A, T377Q, S379C, K390R, A400T, E404D, I434L, V435T, A437V, L452V, S468T, T470N, D471E, H483Q, L491S, K512S, S519N, Q524E, K530R, A534S, A554S  
>SK184| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DADFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHREKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKNSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTVEAE
LELAENREILKEPVHGVYYDPPKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRAA
HTNDVKQLTEAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPLTGVETFYVDGAANRETKVGKAGYVTDRGRQKVVTLNETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDSSESELVNQIIEELIKKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Matthews, PC Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol, 2008