<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, D25E, V31I, V37I, M50I, I60V, I72V, F100Y, L101I, T112V, T125A, K136Q, I162V, V201I, T206S, L234I, R269K, D278A V281M, S283G
>SK172| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMASEFNLPPIVAKEIIASCDKCQLKGEAIHGQVDCSPGV
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN
FTSTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIVGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCMAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, E35D, N37H, R41K, L63P, H69K, I93L  
>SK172| codons 1-99
PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEDMHLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V8I, V35T, T39E, S48T, K122E, D123S, I142V, K173A, D177E, T200A, Q207N, R211K, V245Q, E248D, A272P, K277*, L279M, E291D, V292I, I293V, Q334E, G335E, R356K, G359T, K366R, T369A, T377M, T386I, K390R, A400T, E404D, V435A, A437V, L452A, V458I, V467I, S468T, D471E, H483Q, L491S, E492Q, L517I, S519N, K530R, A534S, V548I, A554S H208R, M230V
>SK172| codons 1-560
PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRNRLLKWGFTTPDKKHQKEPPFLWVGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKV*QMCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEEQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVRQLAEAVQKIAMESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGVETFYVDGAANRETKAGKAGYITDRGRQKVITLTETTNQKTELQ
AIQLALQDSGSQVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQIDKLVSSGIRKVL

References
Author Title Citation
Matthews, PC Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol, 2008