<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, R41K, D60E, L63I, H69K, L89M, I93L  
>SK052| codons 1-99
PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE
QIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        T351E, K353Q, A355*, R356V, G359T, V365I, K390R, E396G, A400T, E404D, V435A, A437V, L452I, R461Q, V466I, D471E, T477A, Q480H, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554K, I556V, R557K, K558V, V559I  
>SK052| codons 350-559
KEGQY*VMRTAHTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKGTWETWWTDYWQAT
WIPEWEFVNTPPLVKLWYQLEKEPIAGVETFYVDGAANRETKIGKAGYVTDQGRQKIVSL
TETTNQKAELHAIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKE
RIYLSWVPAHKGIGGNEQVDKLVSKGVKVI

References
Author Title Citation
Matthews, PC Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol, 2008