<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14N, L19I, M36I, R41K, D60E, L63P, H69K, L89I, I93L  
>PS390| codons 1-99
PQITLWQRPLVTINIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39E, S48T, K122E, D123S, K173V, Q174K, D177E, I178L, G196M, T200E, E204K, Q207E, V241I, V245Q, A272P, K277R, Q278H, L279M, E291D, I293V, Q334D, G335D, R356K, G359S, T386I, K390R, A400T, E404D, E413D, I434M, V435A, A437V, L452I, V466I, V467I, S468T, T470N, D471G, T477A, H483Q, L491S, V493A, S519N, K530R, A534S  
>PS390| codons 1-540
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPELVI
YQYMDDLYVGSDLEIMQHREKIEKLREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRHMCKLLRGTKALTDVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPDWEFVNTP
PLVKLWYQLEKEPMAGVETFYVDGAANRETKIGKAGYVTDRGRQKIITLNGTTNQKAELQ
AIQLALQDSGSEANIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK

References
Author Title Citation
Matthews, PC Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol, 2008