Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PS367 | PS367 | South Africa | 2008 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93L |
| >PS367| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39N, S48T, V60I, D123N, K173A, Q174K, D177E, T200A, E203A, L205F, Q207E, F214L, V245Q, A272P, T286A, E291A, V292I, I293V, V317A, Q334D, R356K, G359T, V365I, A371L, T377G, K388R, K390R, A400T, E404D, N447H, V466I, D471E, H483Q, L491S, S519N, K530R, L533M, A534S |
| >PS367| codons 1-540 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIAEFREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTAIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDIKQLTELVQKIAGESIVIWGKTPRFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAAHRETKLGKAGYVTDRGRQKIVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYMSWVPAHK |
References
| Author | Title | Citation |
| Matthews, PC | Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. | J Virol, 2008 |