<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20R, M36I, P39T, R41K, R57K, Q61N, L63Q, H69K, I93L  
>PS117| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEEINLTGKWKPKMIGGIGGFIKVKQYD
NIQIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35K, E36A, T39E, V60I, K122E, D123G, K166T, K173A, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, L452M, S468P, T470S, D471E, Q480H, H483Q, G490E, L491S, S519N, Q524E, E529D, A534S  
>PS117| codons 1-540
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKAICEEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTTILEPFRARNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKMGKAGYVTDRGRQKVVPLSETTNQKTELH
AIQLALQDSESEVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKDKVYLSWVPAHK

References
Author Title Citation
Matthews, PC Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol, 2008