<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6K, V35T, E36A, T39E, S48T, V60I, T69S, K122E, D123G, K173T, Q174K, D177E, T200A, Q207G, R211K, V245K, A272P, T286V, E291D, V292I, I293V, V317A, Q334H, G335D, R356K, M357R, G359A, I375V, T377M, K390R, A400T, E404D, I434M, V435A, A437V, L452I, S468T, L469I, D471E, H483Q, L491P, V496I, S519N, Q524E, K530R, A534S, A554S  
>PS001| codons 1-560
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRAA
HTNDVKQLTEAVQKVAMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPMAGVETFYVDGAANRETKIGKAGYVTDRGRQKVVTITETTNQKTELQ
AIQLALQDSGPEVNIITDSQYALGIIQAQPDKSESELVNQIIEELIKKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, M36V, N37S, P39Q, L63S, H69K, V82I, I93L  
>PS001| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEVSLQGRWKPKMIGGIGGFIKVRQYD
QISIEICGKKAIGTVLVGPTPINIIGRNLLTQLGCTLNF

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E10A, K14R, D25E, V31I, K34R, L45I, M50T, I72V, L74I, E96D, F100Y, L101I, T112V, S119T, T124A, T125A, K136Q, V201I, T218M, L234I, A265V, R269K, D278A S283G
>PS001| codons 1-288
FLDGIDKAQAEHERYHSNWRAMASEFNLPPIVAREIVASCDKCQIKGEATHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQDTAYYILKLAGRWPVKVIHTDNGTN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIMKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGADCVAGRQDED

References
Author Title Citation
Matthews, PC Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol, 2008