Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A284 | A284 | South Africa | 2009 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181C | V179D | T27I, V35T, E36A, T39E, S48T, V90I, K103R, K122E, D123S, T139A, S162C, T200A, Q207E, R211K, F214L, V245Q |
| >A284| codons 1-262 PISPIETVPVKLKPGMDGPKVKQWPLIEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIDI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19I, M36I, R41K, D60E, L63T, H69K, L89M, I93L |
| >A284| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| van Zyl, GU | Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the western cape, South Africa. | J Med Virol, 2011 |