<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219HQ Y181I   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I132V, I135IV, K173A, Q174K, D177E, I178L, T200A, Q207A, R211K, F214L, H221Y, V245Q  
>A198| codons 1-259
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTVPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPELVI
IQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGLTTPDQKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19V, E35D, M36I, R41K, H69K, T74S, L89M, I93L  
>A198| codons 1-99
PQITLWQRPLVTIKVGGQVKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
van Zyl, GU Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the western cape, South Africa. J Med Virol, 2011