Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A178 | A178 | South Africa | 2009 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y188LR | K32KR, V35T, E36A, T39E, S48T, V90I, K122E, D123G, Q145C, S162A, K173T, D177E, T200TA, Q207E, R211RK, F214L, V245Q | F160FV, I244IT |
| >A178| codons 1-257 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYCYNVLPQGWKGSPAIVQASMTKILEPFRTQNPEIVI YQYVDDLRVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPTQLPEKDSWTVNDI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, K20R, M36I, R41K, K45R, L63T, C67A, H69K, V77I, V82I, L89M, I93L |
| >A178| codons 1-99 PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYD QITIEIAGKKAIGTVLIGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| van Zyl, GU | Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the western cape, South Africa. | J Med Virol, 2011 |