<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y188LR   K32KR, V35T, E36A, T39E, S48T, V90I, K122E, D123G, Q145C, S162A, K173T, D177E, T200TA, Q207E, R211RK, F214L, V245Q F160FV, I244IT
>A178| codons 1-257
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYCYNVLPQGWKGSPAIVQASMTKILEPFRTQNPEIVI
YQYVDDLRVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPTQLPEKDSWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, K20R, M36I, R41K, K45R, L63T, C67A, H69K, V77I, V82I, L89M, I93L  
>A178| codons 1-99
PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYD
QITIEIAGKKAIGTVLIGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
van Zyl, GU Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the western cape, South Africa. J Med Virol, 2011