<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, M184V   Y181C   I31IL, V35T, T39E, S48T, K122E, D123S, I132IL, K166R, K173T, D177E, Q197P, T200A, I202V, Q207K, R211A, V245Q  
>A142| codons 1-256
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVI
CQYVDDLYVGSDLEIGPHRAKVEELRKHLLAWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVND

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10M, T12S, I15V, L19V, K20M, E35D, M36I, P39Q, R41K, L63V, H69K, L89M, I93L  
>A142| codons 1-99
PQITLWQRPMVSIKVGGQVMEALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
van Zyl, GU Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the western cape, South Africa. J Med Virol, 2011