Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A140 | A140 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, M184V | Y181C | I31IL, V35T, E36A, T39E, S48T, V60VI, K122E, D123S, I142IT, K173A, D177E, T200A, Q207E, R211K, V245Q |
| >A140| codons 1-257 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTAICEEMEKEGKITKIGPENPYNTPI FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19T, M36I, R41K, L63P, H69K, L89M, I93L |
| >A140| codons 1-99 PQITLWQRPLVSIKIGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| van Zyl, GU | Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the western cape, South Africa. | J Med Virol, 2011 |