Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| GT00349623 | GT00349623 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | K101E, V106M, G190A | V35T, T39E, K43R, S48T, V60I, K122E, I135IK, K173A, D177E, I178M, T200A, Q207E, V245Q, A272P, Q278QH, R284RG, E291D, V292I, I293V, V317A | V254VA, K281*R |
| >GT00349623| codons 1-322 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEREGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAYFSVPL DEDFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEMVI YQYVDDLYVASDLEIGQHRAKIEELREHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTANDIQKLVGKLNWASQIYPGIKVKHLCRLLGGTKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPS |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, L19V, M36I, R41K, L63V, H69K, V82I, L89M, I93L |
| >GT00349623| codons 1-99 PQITLWQRPLVTIRVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Sigaloff, KC | Accumulation of HIV drug resistance mutations in patients failing first-line antiretroviral treatment in South Africa. | ARHR, 2011 |