<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   E36A, T39E, S48T, K122E, D123N, T139K, K173T, Q174N, D177E, I178M, T200A, I202V, R211K, V245Q, A272P, K277R, L283I, I293V, P294T Q207I
>GT00173303| codons 1-308
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTNNPEMVI
YQYVDDLYVGSDLEIGQHRAKVEELRIHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVVTLTEEAE
LELAENRE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35N, M36I, N37E, R41K, D60E, Q61E, I62V, H69K, L89M, I93L  
>GT00173303| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLENIELPGKWKPKMIGGIGGFIKVRQYE
EVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sigaloff, KC Accumulation of HIV drug resistance mutations in patients failing first-line antiretroviral treatment in South Africa. ARHR, 2011