<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, G16GE, L19V, M36I, R41K, L63Q, H69K, L89M, I93L  
>GT00135141_1| codons 1-99
PQITLWQRPLVTIKVEGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIQIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70KR, M184V   K103N, V106M   V35T, T39E, S48T, K122E, D123S, I135T, T139R, I142T, T165I, K173A, Q174K, T200A, Q207A, F214FL, V245Q, A272P, K277R, E291D, V292I, I293V, E297Q  
>GT00135141_1| codons 1-312
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNERPGTRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAKNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTQEAE
LELAENREILKE

References
Author Title Citation
Sigaloff, KC Accumulation of HIV drug resistance mutations in patients failing first-line antiretroviral treatment in South Africa. ARHR, 2011