<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H P14PT, G18GA, V35T, T39E, S48T, V60I, K122E, D123S, I135L, E138Q, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, E291D, V292I, I293V M16MK, D17DY
>GP00022848_2| codons 1-321
PISPIETVPVKLKTGKYAPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSLNNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, R41K, R57K, Q61N, L63P, H69K, L89M, I93L  
>GP00022848_2| codons 22-99
ALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDNIPIEICGKKAIGTVLVGPTP
VNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sigaloff, KC Accumulation of HIV drug resistance mutations in patients failing first-line antiretroviral treatment in South Africa. ARHR, 2011