<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20I, E35Q, M36I, R41K, R57K, L63Q, C67E, H69K, V82I, L89M  
>HP35| codons 1-99
PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYD
QIQIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, V35T, K49R, V60I, K104R, K122E, D123N, E169D, K173T, Q174K, D177E, I178M, T200A, Q207E, R211Q, V245Q, E291D, V292I, I293V, P294T, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A376S, T386V, K390R, Q394R, A400V, K431T, V435L, F440Y  
>HR35| codons 1-440
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEAVQKISTESIVIWGKVPKFRLPIRKETWEVWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPILGAETY

References
Author Title Citation
Ajoge, HO Drug resistance pattern of HIV type 1 isolates sampled in 2007 from therapy-naive pregnant women in north-central Nigeria. ARHR, 2012