<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 EFV+NRTI 54

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N T215L, K219E   V179D S68G, D86E, K103R, V118I, K122E, S162C, G196E, T200A, E204Q, Q207E, R211K, F214L, I244V, V245K, A288S, I293V, E297K, K311KR, I326V, Q334E, A360AT, A376S, T377R, K390R, A400T, T403TI, E404ED, V467I, S468P, T470A, H483Y, L517LV, S519SN, Q524KR, K527NS, A554S K476*Q
>251853G_wk54| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNGTKWRKLVDFRELNKRTQEFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIDI
YQYMDDLYVGSDLEIEQHRAKIEQLREHLLKWGLLTPDEKHQKEPPFLWMGYELHPDKWT
VQPVKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKSLTEVVPLTKEAE
LELAENREILREPVHGVYYDPSKDLVAEIQKQGEGQWTYQIYQEPFKNLKTGKYARMRGT
HTNDVKQLTEAVQKISRESIVIWGKTPKFRLPIQKETWETWWIDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVIPLADTTNQQTELQ
AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESEVVNQIIERLISKEKVYLAWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Brehm, JH Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase. JAIDS, 2011
Riddler, SA Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med, 2008