Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 89079 | 610834Lb | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 2 |
| 2 | None | 11 |
| 3 | 3TC+AZT+NVP | 9 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| S48T, K103R, K122E, S162C, Q174K, Q207E, R211K, A272S, T286A, I293IV, E297A, E312T, G335E, R356K, M357V, E404D, V435VA, K454R, T470A, H483Y, L491S, Q507H, K512R, L517I, S519N, V531I |
| >610834Lb| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKKNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPLTAEAE LELAENREILKTPVHGVYYDPSKDLIAEIQKQGQEQWTYQIYQEPFKNLKTGKYAKVRGA HTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGRAGYVTDRGRQKVVSLADTTNQKTELQ AIYLALQDSGSEVNIVTDSQYALGIIHAQPDRSESEIVNQIIEQLIKKEKIYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Brehm, JH | Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase. | JAIDS, 2011 |
| Riddler, SA | Class-sparing regimens for initial treatment of HIV-1 infection. | N Engl J Med, 2008 |