<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF 3
2 None 3
3 3TC+D4T+EFV 2

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184I   V106M E138K V35T, T39E, K122E, D123S, I135R, I142V, K173A, Q174K, D177E, G196D, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, P345Q, R356K, G359T, T377L, S379C, K390R  
>64042w8| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSRNNKTPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYIDDLYVGSDLEIDQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEQFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIALECIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, K70R, L89M, I93L  
>64042w8| codons 1-99
PQITLWQRPLVAIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Riddler, SA Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med, 2008