<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 EFV+LPV 84

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I T12A, E35D, R41K, L63P, A71T, I93L  
>RG52107w84| codons 1-99
PQITLWQRPLVAIKIGGQLKEALLDTGADDTVIEDMNLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGHKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   V35T, V60I, I135T, I142V, E169D, I178L, V245E, E248K, A272P, I293V, E297K, A304AE, I326V, Q334R, G335D, M357T, I375V, T377L, S379C, K390R  
>RG52107w84| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDLVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPKKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE
LELEENREILKEPVHGVYYDPSKDLVAEIQKQGRDQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKVALECIVIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Riddler, SA Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med, 2008