<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 EFV+LPV 12

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q18L, N37S, R41K, I62V, L63A, I64L, A71T, V77I, I93L  
>RG48271w12| codons 1-99
PQITLWQRPLVTIKIGGLLKEALLDTGADDTVLEEMSLPGKWKPKMIGGIGGFIKVRQYD
QVALEICGHKTIGTVLIGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   V35T, T39A, E40D, D123E, S162C, K173R, Q207K, R211K, P243T, V245M, A272P, K277R, T286A, V292I, I293V, V365I, A376S, T377I, V381I, K390R I5IF
>RG48271w12| codons 1-394
PISPFETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRRQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRKHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQTIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDIKQLTEAVQKISIESIIIWGKTPKFRLPIQ

References
Author Title Citation
Riddler, SA Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med, 2008