<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+LPV 67

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       K20R, V60I, K64R, Q174N, A272P, K277R, T286V, V292I, E297R, K311R, I326V, G333E, R356K, R358K, Q373H, K390R  
>RG31923w67| codons 1-400
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKNNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGVKALTEIIPLTREAE
LELAENREILREPVHGVYYDPSKDLVAEIQKQEQGQWTYQIYQEPFKNLKTGKYAKMKGA
HTNDVKQLTEAVHKIATESIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  K43T T12P, I13V, L33V, L63S, I64V, C67Y  
>RG31923w67| codons 1-99
PQITLWQRPLVPVKIGGQLKEALLDTGADDTVVEEMNLPGRWTPKMIGGIGGFIKVRQYD
QISVEIYGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Riddler, SA Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med, 2008