<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 EFV+LPV 108

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    P39Q, I62V, L63T, A71V, I72IT, I93L  
>RG21379w108| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLQGRWKPKMIGGIGGFIKVRQYD
QVTIEICGHKVTGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70KR       I135T, Q174H, Q197E, I202V, R211K, V245M, T286A, A288S, I293V, E297A, I309V, V317A, T338S, M357T, T369S, K390R, A400S  
>RG21379w108| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKHNPDIVI
YQYMDDLYVGSDLEIGEHRTKVEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKSLTEVVPLTAEAE
LELAENREVLKEPVHGAYYDPSKDLIAEIQKQGQGQWSYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLSEAVQKIATESIVIWGKTPKFRLPIQKETWES

References
Author Title Citation
Riddler, SA Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med, 2008