<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, K14R, I15V, L19I, M36I, N37K, R41N, H69K, T74S, L89M, I93L  
>SC107| codons 2-99
QITLWQRPVVTIRVGGQIKEALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVRQYDQ
ILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L T215L G190A A98G V35T, T39N, K122E, D123N, I135M, K173T, V179I, Q197K, T200E, Q207A, R211K, V245Q, D250E, A272P, K277R, E291D, I293V N137S
>SC107| codons 1-312
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSMNSETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIII
YQYMDDLYVASDLEIGKHREKIEELRAHLLKWGFLTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVVPLTEEAE
LELAENREILKE

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D25E, V31I, V32I, M50T, L101I, T112V, T124N, G134D, K136Q, D167E, V201I, L234I, R269K, D278A V281M
>SC107| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIIAKEIVASCDKCQLKGEATHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSNTVKAACWWADIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCMASRQDED

References
Author Title Citation
Graf, T HIV-1 genetic diversity and drug resistance among treatment naive patients from southern Brazil: An association of HIV-1 subtypes with exposure categories. J Clin Virol, 2011