<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D25E, V31I, V32I, L45V, L101V, T112V, S119P, T124N, K136Q, V165I, V201I, I203M, T218I, L234I, I251L, A265V, R269K, D278A D288N
>SC96| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASEFNLPPIIAKEIVASCDKCQVKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFVLKLAGRWPVKVIHTDNGPN
FTSNTVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQIRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVLQDNSDIKVVPRRKVKIIKDYGKQMAGADCVASRQDEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13V, I15V, G16E, M36I, N37K, R41N, L63H, H69K, L89M, I93L  
>SC96| codons 4-99
TLWQRPLVAVKVEGQLKEALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVRQYDQIH
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K32R, V35S, E36A, T39E, K122E, I135T, I142M, A158S, K173T, Q174R, T200A, Q207A, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
>SC96| codons 1-309
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALSAICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGMRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTRNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREI

References
Author Title Citation
Graf, T HIV-1 genetic diversity and drug resistance among treatment naive patients from southern Brazil: An association of HIV-1 subtypes with exposure categories. J Clin Virol, 2011