Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SC52 | SC52 | Brazil | 2008 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E138V | E11D, K14R, D25E, V31I, M50T, L101I, T112V, S119T, T124N, T125A, K136Q, V201I, T206S, T218I, L234I, I251L, A265V, R269K, D278A | A133Q, V281M, D288E |
| >SC52| codons 1-288 FLDGIDKAQEDHERYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGTN FTSNAVKAACWWQGIQQVFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVLQDNSDIKVVPRRKVKIIKDYGKQMAGADCMASRQDEE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37K, R41N, H69K, T74S, L89M, I93L |
| >SC52| codons 16-99 GGQLKEALLDTGADDTVLEEMKLPGNWKPKMIGGIGGFIKVRQYDQILIEICGKKAIGSV LVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39D, S48T, D121H, K122E, K166R, K173T, D177E, T200A, E204D, Q207K, R211K, L228S, V245Q, W252R |
| >SC52| codons 1-256 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEDLRKHLLKWGFTTPDKKHQKEPPFSWMGYELHPDKWT VQPIQLPEKDSRTVND |
References
| Author | Title | Citation |
| Graf, T | HIV-1 genetic diversity and drug resistance among treatment naive patients from southern Brazil: An association of HIV-1 subtypes with exposure categories. | J Clin Virol, 2011 |