<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  E138V E11D, K14R, D25E, V31I, M50T, L101I, T112V, S119T, T124N, T125A, A133Q, K136Q, V201I, T206S, T218I, L234I, I251L, A265V, R269K, D278A V281M, D288E
>SC52| codons 1-288
FLDGIDKAQEDHERYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEATHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGTN
FTSNAVKAACWWQGIQQVFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVLQDNSDIKVVPRRKVKIIKDYGKQMAGADCMASRQDEE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    N37K, R41N, H69K, T74S, L89M, I93L  
>SC52| codons 16-99
GGQLKEALLDTGADDTVLEEMKLPGNWKPKMIGGIGGFIKVRQYDQILIEICGKKAIGSV
LVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39D, S48T, D121H, K122E, K166R, K173T, D177E, T200A, E204D, Q207K, R211K, L228S, V245Q, W252R  
>SC52| codons 1-256
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEDLRKHLLKWGFTTPDKKHQKEPPFSWMGYELHPDKWT
VQPIQLPEKDSRTVND

References
Author Title Citation
Graf, T HIV-1 genetic diversity and drug resistance among treatment naive patients from southern Brazil: An association of HIV-1 subtypes with exposure categories. J Clin Virol, 2011