<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    V37I, D41N, L45I, I84L, S119P, T122I, T124A, T125A, K136N, M154I, V165I, V201I, A205S, K211R, T218I, L234V, D256E S283G, D288N
>SC44| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIIASCNKCQIKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYLEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGPN
FISAAVKAACWWAGINQEFGIPYNPQSQGVVESINKELKKIIGQIRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIISTDIQTRELQKQIIKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, M36I, R41K, K45R, R57K, Q61N, H69Y, I72T, L89M  
>SC44| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYDNIL
IEICGYKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, I132V, I135V, S162C, E169D, K173A, Q174K, T200A, Q207K, R211K, V245Q, E248D, W252R  
>SC44| codons 1-256
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTVPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRKHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSRTVND

References
Author Title Citation
Graf, T HIV-1 genetic diversity and drug resistance among treatment naive patients from southern Brazil: An association of HIV-1 subtypes with exposure categories. J Clin Virol, 2011