Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LB3-P52 | P52-0 | U.S. | 1998 | HIV1 | B | Plasma | MMC |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S, A158S, N175H, T200V |
| >P52-0| B07 | codons 1-229 | clone B07 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEEKISKIGPENPYNTPV FAIKKKGSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B08 | codons 1-229 | clone B08 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPVNPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B04 | codons 1-229 | clone B04 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRSKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B06 | codons 1-229 | clone B06 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B05 | codons 1-229 | clone B05 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIEQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B03 | codons 1-229 | clone B03 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B02 | codons 1-229 | clone B02 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW >P52-0| B01 | codons 1-229 | clone B01 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRTKVEELRQHLLRWGFATPDKKHQKEPPFLW >P52-0| codons 1-229 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQHPDIVI YQYMDDLYVGSDLEIGQHRVKIEELRQHLLRWGFTTPDKKHQKEPPFLW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, H69Y |
| >P52-0| B04 | codons 1-99 | clone B04 PQITLWQRPLVSIKIGGQIKEALFDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B06 | codons 1-99 | clone B06 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B05 | codons 1-99 | clone B05 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B01 | codons 1-99 | clone B01 PQITLWQRPLVSIKIGGRIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B07 | codons 1-99 | clone B07 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B02 | codons 1-99 | clone B02 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B08 | codons 1-99 | clone B08 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIIIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| B03 | codons 1-99 | clone B03 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF >P52-0| codons 1-99 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Bacheler, LT | Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy. | AAC, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |