<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA7101 CA17570 U.S. 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 139
2 3TC+AZT+RTV+SQV 154

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, G48T, I54V, V82A, I84V L24I L10I, T12TI, I13V, G16E, K20I, L63T, I72T, T74S, V77I, L89M, T91A  
>CA17570| codons 1-99
PQITLWQRPIVIVKIEGQLIEALIDTGADDTVLEEMNLPGRWKPKLITGIGGFVKVRQYD
QITIEICGHKATGSVLIGPTPANVIGRNMLAQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y       K43E, E44A, K64KR, V118I, D121Y, K122E, I135T, S162C, G196GE, E203K, Q207E, R211K, L228H, A272P, T286A, A288AT, E297Q I167M
>CA17443| codons 1-303
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPV
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKMLEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRTKIKELREHLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTEVIPLTQEAE
LEL

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005