Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7082 | CA17546 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 190 |
| 2 | AZT+D4T | NA |
| 3 | 3TC+AZT+D4T+SQV | 5 |
| 4 | 3TC+D4T+SQV | 185 |
| 5 | 3TC+D4T | 14 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10LI, K14KR, L19Q, E35D, D60E, Q61E, L63P, A71V, I93L |
| >CA17546| codons 1-99 PQITLWQRPIVTIRIGGQQKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYE EIPIEICGHKVISTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219E | K154E, S162A, G196GR, R211K, F214L, A272P, K275KN, K277R | A129AG, I132IR, I142GV |
| >CA17421| codons 1-285 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTGFTRPSINNETPGGRYQYNVLPQGWEGSPAIFQASMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIRQHRTKIEELRQHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGINVRQLCKLLRG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |