<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D3E, R20K, V31I, I72V, L74I, T112I, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, H171Y, V201I, L234I, S255N  
>CY058| codons 1-288
FLEGIDKAQEEHEKYHSNWKAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKIVHTDNGPN
FTSSAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEYLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNNDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q2P, I13V, E35D, M36I, R41K, R57G, H69K, L89M, I93L V75E
>CY058| codons 1-99
PPITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVGQYD
QILIEICGKKAIGTELVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11T, T27A, E28K, V35T, S68G, K122E, D123S, A158S, K173L, Q174K, D177E, Q207A, R211S, V245T, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, D324E, I326V, R356K, M357K, R358G, G359S, E370A, A371V, I375V, S379G, V381I, K390R, T403M, L452I, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520R, Q524K, K527E, K530R, A534S, A554Y, K558R P1A, W24G, N57D, E79K
>CY058| codons 1-560
AISPIETVPVTLKPGMDGPKVKQGPLAKEKIKALTEICTEMEKEGKISKIGPENPYDTPV
FAIKKKDGTKWRKLVDFRKLNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRLKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKELVAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKKGSA
HTNDVKQLTAVVQKVATEGIIIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKIGKAGYVTDRGRQKVVPLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNRIIEKLIEKERVYLSWVPAHK
GIGGNEQVDKLVSYGIRRVL

References
Author Title Citation
Kousiappa, I Near full-length genetic analysis of HIV sequences derived from Cyprus: evidence of a highly polyphyletic and evolving infection. ARHR, 2009