Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7068 | CA17523 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+SQV | 104 |
| 2 | 3TC+AZT+IDV | 26 |
| 3 | ABC+APV+EFV | 57 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | F53L, Q58E | L10IM, I15V, K20R, M36I, N37D, L63P, I64V, T74K, I93L | L5LR |
| >CA17523| codons 1-99 PQITRWQRPIVTIKVGGQLREALLDTGADDTVLEEIDLPGRWKPKLIGGIGGLVKVREYD QIPVEICGHKAIGKVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, L210W, T215Y | K219N | K103N, Y181C, G190A | V179F | T39A, K43E, E44A, K101KR, V111I, V118I, K122KE, I135T, D177DE, Q207QE, H208Y, R211K, L228HR, V245M, A272P, K277R |
| >CA17397| codons 1-291 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEEAGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDIGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIFI CQYMDDLYVASDLEIGQHRTKIEELREYLWKWGFYTPDNKHQKEPPFHWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |