Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4093 | CA17504 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+SQV | 56 |
| 2 | D4T+DDI | 13 |
| 3 | 3TC+AZT+IDV | 21 |
| 4 | 3TC+D4T+NVP | 47 |
| 5 | 3TC+DDI+NFV | 30 |
| 6 | ABC+RTV+SQV | 38 |
| 7 | Unknown | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L10I, K20R, E35D, M36I, I62V, L63S, I64V |
| >CA17504| codons 8-99 RPIVTIKIGGQLREALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYDQVSVEIC GHKAIGTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, T215Y | L100I, K103N | A98G | K20R, S48T, K122E, V245M, I293V, E297K |
| >CA17379| codons 1-297 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGIKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTK |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |