Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7087 | CA17427 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 109 |
| 2 | 3TC+AZT | 30 |
| 3 | 3TC+D4T+DDI | 30 |
| 4 | 3TC+D4T+NFV | 175 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | V35T, K49KR, V60I, D123E, I135T, V179I, G196E, F214L, D218E, V245M, K249Q | R143RK |
| >CA17427| codons 1-263 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIKYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVGSDLEIEQHRTKIEELRQHLLRWGLTTPEQKHQKEPPFLWMGYELHPDKWT VQPIMLPEQDSWTVNDIQKLVGK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | Q58E | L10V, I13V, K20I, M46X, I62V, L63P, V77I |
| >CA17577| codons 1-99 PQITLWQRPVVTVKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKXIGGIGGFIKVREYD QVPIEICGHKAIGTVLIGPTPVNIIGRSLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |