Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7078 | CA17416 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 83 |
| 2 | 3TC+AZT | 96 |
| 3 | 3TC+AZT+IDV | 52 |
| 4 | NVP+RTV+SQV | 105 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN, Y181C | V108I | V35VA, K49R, T69N, K102Q, D123E, I135IV, K166I, I178L, H221HY, E224ED, T240TP, K277R, Q278H, I293V | K281KE, A299AG |
| >CA17416| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALAEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTILDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTIILEPFRKQNPDLVI CQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKYQKDPPFLWMGYELHPDKWP VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRHLCELLRGTKALTEVVPLTEEGE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13IV, I15IV, I72IV, I93IL |
| >CA17541| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKAVGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |