Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RG291 | RG291w47 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ABC+AZT | 47 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | R83RK, A98AS, D123E, I178L, V179I, I195IL, T200AE, I202V, Q207K, R211S, V245E |
| >RG291w47| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHP SGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDLIIYQYVDDLYVGSDLELGQHREKVEELRKHLLSWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, M36I, N37NS, R57K, L63P, I72IT |
| >RG291w47| codons 4-99 TLWQRPLVTIKVGGQLKEALLDTGADDTVLEEISLPGRWKPKMIGGIGGFIKVKQYDQIP IEICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gulick, RM | Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection. | N Engl J Med, 2004 |