Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3914 | CA17378 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 111 |
| 2 | AZT+DDC | 39 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+D4T | 37 |
| 5 | AZT+DDI+NFV | 77 |
| 6 | 3TC+AZT+EFV+NFV | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69D, K70R, M184V | D67G | K103KN, Y188YFHL | A98G | K64R, I135IM, I142V, G196E, R211A, F214L, V245M, Q278E, I293V, E297K | N136ND, T253TP |
| >CA17378| codons 1-298 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKGSDRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSMDNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLLVGSDLEIEQHRTKIEELRQHLLAWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWPVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGTKALTEVVPLTKE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L33I, T74P | R41K, I62V, L63P, H69HY, A71T, I72V, V77I, I93L |
| >CA17503| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEMNLPGKWKPKIIGGIGGFIKVRQYD QVPIEICGYKTVGPVLIGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |