Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE7108 | SE7108 | Sweden | 1994 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 152 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | K219Q | V35T, V60I, D121H, K122E, D123E, I135T, K173S, Q174K, D177E, I178L, V179I, T200I, Q207E, R211K, K238R, V245K, D250E, L282C, T286A, V292I, I293V, G335D, T338S, P345Q, F346Y, R356K, M357L, A360T, V365I, E370A, T377Q, S379C, K390R, A400T, E432D, V435A, A437V, V458I, H483N, L491P, K512R, S519N, Q524K, K527G, E529D, A534S, A554S |
| >SE7108| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPELII YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFYTPDQKHQKEPPFLWMGYELHPDRWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKCLRGAKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWSYQIYQEQYKNLKTGKYAKLRGT HTNDIKQLTAAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAGVETFYVDGAANRETKLGKAGYITDRGRQKVVSLTDTTNQKTELQ AINLALQDSGPEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, R57K, H69K, L89M |
| >SE7108| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, I72V, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, Q216H | S283G |
| >SE7108| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKHITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Carr, JK | Characterization of subtype A HIV-1 from Africa by full genome sequencing. | AIDS, 1999 |