<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AHHC9 HolgHC9 Spain 1998 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G17E, L19I, K20I, E35Q, M36I, R41K, R57K, C67E, H69K, V82I, L89M, N98I  
>HolgHC9| codons 9-99
PLVTVKIGEQIIEALLDTGADDTVLEQINLPGKWKPKMIGGIGGFIKVKQYDQILIEIEG
KKAIGTVLVGPTPINIIGRNMLTQIGCTLIF

References
Author Title Citation
Holguin, A Protease gene analysis of HIV Type 1 non-B subtypes in Spain. ARHR, 2000
Holguin, A Heterogeneous nature of HIV-1 recombinants spreading in Spain. J Med Virol, 2005
Holguin, A Impact of frequent natural polymorphisms at the protease gene on the in vitro susceptibility to protease inhibitors in HIV-1 non-B subtypes. J Clin Virol, 2004