Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| EC15 | EC15F | U.S. | 1995 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | 24 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q207E, R211K, V245M, I293V, E312N, I326V, I329V, G333E, M357T, A376S, V381I, K390R, K395R, D460N, R461K, V467I, L469I, L491S, A554T, K558R |
| >EC15F| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKNPVHGVYYDPSKDLVAEVQKQEQGQWTYQIYQEPFKNLKTGKYARTRGA HTNDVKQLTEAVQKISTESIIIWGKTPKFRLPIQRETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVISITDTTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGIRRVL |
References
| Author | Title | Citation |
| Coakley, EP | Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine. | AIDS, 2000 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |