Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| EC10 | EC10F | U.S. | 1995 | HIV1 | B | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | 24 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, T69S, D177E, V245K, E248D, D250E, A272P, K277R, T286A, I293V, K347Q, S379G, T403I, E404D, S468P, S519N, K527N |
| >EC10F| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFQNLKTGKYARMRGA HTNDVKQLTEAVQKIATEGIVIWGKTPKFKLPIQKETWEAWWIDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTDTTNQKTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Coakley, EP | Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine. | AIDS, 2000 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |