<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, S24N, V31I, V37I, M50I, I60V, I72V, I84M, L101I, K111R, T112V, I113V, T124A, T125A, G134N, K136Q, D167E, V201I, K211R, T218I, L234I S283G
>MBTB047| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMANDFNLPPIVAKEIIASCDKCQLKGEAIHGQVDCSPGV
WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVRVVHTDNGSN
FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16E, K20R, E35D, M36I, P39S, R41K, I62V, L63T, E65D, H69K, L89M  
>MBTB047| codons 1-99
PQITLWQRPLVTIKIEGQLREALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVRQYD
QVTIDICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I5V, L34I, V35T, T39N, I50V, V60I, D123E, I142V, K173A, D177E, T200A, Q207A, R211K, V245K, D250E, S251N, T286A, E291D, V292I, I293V, P294T, E297K, E312D, R356K, M357R, R358K, G359S, T369A, A371V, I375V, A376T, T377M, K390R, E399D, A400T, E432D, V435M, R461K, S468T, D471E, Q480H, H483Y, K512R, L517I, S519N, Q524K, K527E, A534S, V548I, A554S  
>MBTB047| codons 1-560
PISPVETVPVKLKPGMDGPKVKQWPLTEEKIKAITEICNEMEKEGKISKVGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKENWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTKEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKRKSA
HTNDVKQLAEVVQKVTMESIVIWGKTPKFRLPIQKETWDTWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIMGAETFYVDGAANRETKLGKAGYVTDKGRQKVVTLTETTNQKTELH
AIYLALQDSGLEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKEKVYLSWVPAHK
GIGGNEQIDKLVSSGIRKVL

References
Author Title Citation
Vidal, N Genetic characterization of eight full-length HIV type 1 genomes from the Democratic Republic of Congo (DRC) reveal a new subsubtype, A5, in the A radiation that predominates in the recombinant structure of CRF26_A5U. ARHR, 2009